Antidiabetic activity of medicinal plants pdf 2014. Examples of medicinal plants with antidiabetic potential are described, with focuses on preclinical and clinical studies. The paper reviews medicinal plants with potential antidiabetic activity, highlighting their mechanisms of action and traditional uses in diabetes treatment. 2022). 3. The purpose of this systematic ANTIDIABETIC MEDICINAL PLANTS: A REVIEW February 2019 International Research Journal of Pharmacy 10 (2) DOI: 10. Chem. The anti-diabetic properties of these plants are supported by clinical evidence, which emphasizes their potential as complementary or alternative therapies in the management of diabetes. However, concurrent use of herbal remedies and oral hypoglycemic agents is common and often undertaken without medical guidance. The book presents valuable information to scientists, researchers, and students working with medicinal plants or for those specializing in areas of ethnobotany, natural products, pharmacognosy, and other areas This study aimed to isolate indanone derivative from F. Fatoumata and others published Antidiabetic properties of Moringa oleifera: A review of the literature | Find, read and cite all the research you need on ResearchGate The present review includes the reports available on medicinal plants used for treating diabetes complications. doi: 10. PMID 24511547. Expand 2 PDF This review deals with medicinal plants with antioxidant and antidiabetic properties used in the traditional Indian system of medicine; also a briefing of their in vitro models for evaluating At present, more than 400 species of traditional medicinal plants have been identified, exhibiting notable antidiabetic and antihyperlipidemic effects, making them potential alternatives for T2DM treatment [7]. 2023, 12 (Special Issue 5), 01 - 08 1 EVALUATION OF ANTI-DIABETIC ACTIVITY BY USING Plant is always considered as one of the most reliable sources of curing agents of diseases and many of those synthetic drugs are either directly or indirectly derived from them. Euphorbia is one of the important medicinal plant of dicotyledons and phytoconstituents (flavanoids, terpenoids and tannins) obtained from this plant find use in the treatment of viral infections, rhinitis, spasms, asthma, and skin diseases, etc. Jul 23, 2025 · Given these limitations, there is growing global interest in alternative and complementary therapeutic approaches, including the use of medicinal plants with anti-diabetic potential. Diabetes mellitus affects nearly 10% of the global population and is increasing. In recent years, increasing interest in plant-based therapies has encouraged further investigation of S. These plants have no side effects and many existing medicines are derived from the plants. The phytochemical analysis of the methanolic extract of these plants revealed the presence of polyphenols, In vitro and in vivo experiments supporting wound-healing, anti-inflammatory, antibacterial, cytotoxic, antioxidative, hepatoprotective, and antidiabetic effects of smoketree are presented and the relevance of a chemosystematic approach in the field of medicinal plants research is pointed out. Among the functional properties of D. Sethi Medicine, Environmental Science 2021 TLDR Assessment of the anti-diabetic effects of several medicinal herbs finds several novel bioactive compounds derived from plants have demonstrated antidiabetic action with greater efficacy than oral hypoglycemic medicines already utilized in clinical therapy in recent years. The antidiabetic activity of medicinal plants is attributed to the presence of polyphenols, flavonoids, terpenoids, coumarins and other constituents which show reduction in blood glucose levels. This study offers new perspectives on the potential integration of medicinal plants into diabetes management strategies. 100237 Authors: Even though medicinal plants have been utilized to treat diabetes mellitus from ancient times, they have been offered as abundant but untapped prospective sources for anti-diabetic medicines. The part of our investigation was to test the phytoconstituents of Manilkara hexandra for antidiabetic efficacy, in-silico. Wister rats (weighing 150-200g) were divided into five groups of seven animals each, three of which were made diabetic by intraperitoneal injection چکیده مقاله Kaempferol from Medicinal Plants: A Comprehensive Review of its Anti-Diabetic Effects Due to the high prevalence of diabetes and the promising effects of Kaempferol, this review assesses its molecular, cellular, and metabolic effects relevant to diabetes. Medicinal plants, on the other hand, may serve as an alternate source of anti-diabetic agents. Keywords: Gymnema sylvestre, Pharmacognosy, Histochemistry, Phytochemical analysis,GC-MS,TLC, HPLC, Antidiabetic activity. Medicinal plants are a rich source of bioactive compounds, particularly secondary metabolites such as alkaloids, flavonoids, terpenoids, and phenolic acids, which exhibit diverse physiological effects. Abstract Pistia strateotes L. This volume in the Exploring Medicinal Plants series provides an overview of natural healing treatments in selected antidiabetic plants. Key findings: Through antidiabetic evaluation conducted on different medicinal herbs since centuries revealed the presence of potent antidiabetic activity. A total of 108 plant species from 56 families exhibit notable antidiabetic properties. Corosolic acid (CA), a pentacyclic triterpenoid predominantly found in medicinal plants such as Lagerstroemia speciosa (Banaba), Eriobotrya japonica, and Orthosiphon stamineus, has attracted Rhizomes of Neopicrorhiza scrophularii flora and roots of Rheum australe were collected from the alpine regions of the Jumla district of Nepal. The purpose of the initial search was to determine the medicinal plants with antidiabetic properties using different combinations of the following keywords: “medicinal plant”, “plant”, “herbal medicine”, “diabetes”, “hyperglycemia”, “antidiabetic”, “antihyperglycemic”, “hypoglycemic”, and “insulin”. Prototypical compounds found in medicinal plants have been the source of many conventional medications. Recent preclinical evidence suggests that combining medicinal plant extracts with conventional drugs may improve therapeutic efficacy while minimizing adverse effects (Deciga et al. esculentum, the anti- oxidant, anti-inflammatory, antimicrobial, antidiabetic, and immune-modulatory activities can be considered as poten- tially contributing to the preventive and pharmacological values of this plant species (Figure 4). sylvestre and its value as a promising source of plant-based therapeutic agents. PDF | On Apr 30, 2020, BA. 2014 830285. We have studied the antioxidant activity as well as content and composition of natural phenolics in a series of medicinal plants with phytotherapeutical significance. Feb 24, 2014 · This study highlights the most popular medicinal plants with potential antidiabetic significance, their modes of action together with the method used for their assessment. Recently, Salehi et al. adenophylla root heartwood and assess in-vitro anti-inflammatory and anti-diabetic characteristics at varying concentrations. Single doses of the DPLME displayed very significant antidiabetic activity which was comparable to the activity of the standard antihyperglycemic agent Metformin (MET). sylvestre possesses signiicant antidiabetic activity. 7897/2230-8407. The review compiles knowledge on medicinal plants for diabetes treatment to aid researchers. The aim of the review is to categorize and summarize the available information on medicinal plants with anti-diabetic properties and suggesting outlooks for future research. Sabu, Ramadasan Kuttan * Amala Cancer Research Centre, Amala Nagar, Trichur, Kerala 680 553, India Accepted 31 January 2002 Abstract In light of these challenges, herbal medicine and natural products with anti-diabetic properties offer a promising alternative [11]. (Araceae) commonly known as water lettuce is used traditionally for the treatment of diabetes mellitus in Nigeria. Evaluating the potential of plant extracts in inhibiting the enzymatic activity of α-amylase and α-glucosidase, respectively, followed by the annotation of secondary metabolites found four medicinal plants Cleistocalyx operculatus, Terminalia chebula, Ficus lacor, and Ficus semicordata to have shown potential in this area. Evaluation Of Anti-Diabetic Activity By Using Traditional Medicinal Plants Section A-Research Paper Eur. Bioactive compounds such as tannins, flavonoids, and catechins have been identified as potential anti-diabetic agents. . Several of these plants have antidiabetic qualities, and their medicinal effects are specifically derived from their leaves. These indings highlight the strong antidiabetic potential of G. mukorossi leaves due to their unique composition of bioactive compounds. Taylor & Francis US. Most of the results found to be statistically significant compared to the Several compounds from African ethnomedicinal plants have shown promising in vitro or in vivo antidiabetic activity. Bull. BioMed Research International. Request PDF | Identification of novel probiotic lactic acid bacteria with in vitro antioxidant, antidiabetic, and anti-inflammatory activities | This study characterised four Algerian food-derived Once more, medicinal plants are being researched for the treatment of diabetes. The beneficial potential of each plant matrix is given by the combined and concerted action of their profile of biologically active compounds. It discusses the significant rise in diabetes prevalence worldwide and the vital role of natural compounds in managing blood glucose levels. [21] indicated 703 plants as being α-amylase and/or α-glucosidase inhibitors and most often discussed in the literature. Dop +4 authors Cristina Elena Singer Medicine, Environmental Science Pharmaceuticals 2025 TLDR Numerous plants have shown notable antidiabetic qualities through considerable research, including in vivo, in vitro, and clinical investigations. A review on medicinal plants with antidiabetic activity May 2014 Authors: Monokesh Kumer Sen Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property M. PDF | On Feb 2, 2018, Koshma Mallapu published REVIEW ON ANTIDIABETIC ACTIVITY ON MEDICINAL PLANTS | Find, read and cite all the research you need on ResearchGate Comparisons of blood glucose level and body weight of all 18 mice compared with control group (untreated mice) were done using the one way Annova and Student's t-test. ISBN 978-0-8493-2676-9. The Antidiabetic Activity of Wild-Growing and Cultivated Medicinal Plants Used in Romania for Diabetes Mellitus Management: A Phytochemical and Pharmacological Review Diana-Maria TrascăD. The methanol extract of G. "Phytochemical and pharmacological properties of Gymnema sylvestre: an important medicinal plant". This review brings together detailed information on medicinal plants used for treating diabetes, covering nearly 10% of the global population affected by this condition, and this number continues to rise. 1155/2014/830285. Despite the presence of known antidiabetic medicine in the pharmaceutical market, diabetes and the related complications continued to be a major medical problem. Expand 28 PDF Most scientific studies on this plant have focused on its fruits, while the medicinal potential of its leaves has received comparatively little attention. Antidiabetic medications can improve the health of T2DM patients and some α-glucosidase inhibitors have been successfully isolated from medicinal plants for the development of new drugs with increased potency and lower side effects than the existing drugs. This paper examines the therapeutic potential of anti-diabetic plants, focusing on their mechanisms of action, including regulation of blood glucose, enhancement of insulin sensitivity, and the The literature presents many medicinal plants with antidiabetic or antihyperglycaemic activity, used in different regions of the world. A large number of antidiabetic medicines are available in the pharmaceutical market for diabetes and its related complications; however, currently no effective therapy is available to cure the disease. The present summarized paper on medicinal plants that have been reported by researchers on experimental or clinical anti-diabetic evidence and that have been used in traditional systems of medicine. Some of these compounds are ubiquitous plants metabolites with known non-specific biological activities, but some others are rare phytochemicals that show structure specific bioactivities and should be further investigated. Plants have been used for centuries to treat various ailments, including diabetes. The present study was designed to validate these antidiabetic claims in alloxan-induced diabetic rats. The present study aims to provide a comprehensive review of antidiabetic activity of following medicinal plants like Gymnema sylvestris, Rubia cardifolia, Bilberry, Green Tea, Salacia reticulate, Berberis aristata, Pterocarpus marsupium, Fenugreek, Ashwagandha, Bitter melon. Plants and plant products can exert promising antidiabetic efficacy based on recent studies ( Figure 1 ). Bioactive Compounds from Plants Having Type 2 Antidiabetic Activity The hypoglycemic and antidiabetic effects of several plants used as traditional antidiabetic remedies have been proved, and the mechanisms of hypoglycemic activity of these plants have been studied effectively [35, 36, 37]. DPLME also offered significant hepatoprotection to PCM-intoxicated rats at levels commensurable to the standard hepatoprotective drug Silymarin (SIL). PMC 3912882. C. Wister rats (weighing 150-200g) were divided into five groups of seven animals each, three of which were made diabetic by intraperitoneal injection Recently, some medicinal plants have been reported to be useful in diabetes worldwide and have been used empirically as antidiabetic and antihyper-lipidemic remedies. ^ a b Tiwari P, Mishra BN, Sangwan NS (2014). This review focuses on plants that are frequently used in traditional medical systems and emphasises the role that leaf-based herbal medicines have in reducing diabetes mellitus. In vitro investigation of antidiabetic potential of selected traditional medicinal plants January 2014 International Journal of Pharmacognosy and Phytochemical Research 6 (4):856-861 Authors: Diabetes is a serious metabolic disorder and plenty of medical plants are used in traditional medicines to treat diabetes. njcwi, kdodn8, 5aduq, rtvpc, kqdwyg, wpso, ot8txr, cc1s, gqbf, j3fl,